Tg(TcraDN32D3)78Alhn
Transgene Detail
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| Symbol: |
Tg(TcraDN32D3)78Alhn |
| Name: |
transgene insertion 78, Agnes Lehuen |
| MGI ID: |
MGI:3526073 |
| Synonyms: |
Tcra-Va14-Ja281, Tg A14-78, Tg(TcraCD1d1)78Alhn, Valpha14-Jalpha281 Tg, Valpha14Jalpha281 Tg |
| Transgene: |
Tg(TcraDN32D3)78Alhn Location: unknown
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| Alliance: |
Tg(TcraDN32D3)78Alhn page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(TcraDN32D3)78Alhn expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Tcra (MGI:98553) |
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Mutation details: The transgene contains the V-J exon from the rearranged Tcra gene of the C57BL/6-derived, CD1d1-reactive T cell hybridoma DN32D3; this cell line has the Tcra-V14-J281 rearrangement invariably borne by NK1 T lymphocytes.
(J:93798)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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The founder line for this transgene, designated by its creators Tg A14-78, was one of six generated in NOD; the other lines were designated Tg A14-10, -14, -36, -86 and -95.
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| Original: |
J:93558 Lehuen A, et al., Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes. J Exp Med. 1998 Nov 16;188(10):1831-9 |
| All: |
3 reference(s) |
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Analysis Tools
