Gene Expression Data
Assay Details
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Assay
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Reference:
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J:95208
Moore EE, et al., Expression of IL-17B in neurons and evaluation of its possible role in the chromosome 5q-linked form of Charcot-Marie-Tooth disease. Neuromuscul Disord. 2002 Feb;12(2):141-50
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:3525580
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Gene symbol:
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Il17b
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Gene name:
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interleukin 17B
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Probe:
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Il17b cDNA2
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
4A:
postnatal week 4
(more  )
Specimen
4A:
(close  )
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Genetic Background:
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BALB/c
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Age:
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postnatal week 4
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Sex:
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Male
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cerebral cortex |
Present |
Regionally restricted |
4A
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Expression is present in most of the neurons.
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| TS28: hippocampus |
Present |
Regionally restricted |
4A
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Expression is present in most of the neurons.
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Specimen
4B:
postnatal week 4
(more )
Specimen
4B:
(close )
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Genetic Background:
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BALB/c
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Age:
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postnatal week 4
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Sex:
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Male
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Specimen
4C:
postnatal week 4
(more )
Specimen
4C:
(close )
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Genetic Background:
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BALB/c
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Age:
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postnatal week 4
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Sex:
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Male
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: hippocampus CA1 |
Strong |
Regionally restricted |
4C
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Expression is present in the neurons, including those in the hilar region of the hippocampus.
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| TS28: hippocampus CA2 |
Strong |
Regionally restricted |
4C
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Expression is present in the neurons, including those in the hilar region of the hippocampus.
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| TS28: hippocampus CA3 |
Strong |
Regionally restricted |
4C
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Expression is present in the neurons, including those in the hilar region of the hippocampus.
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| TS28: dentate gyrus granule cell layer |
Strong |
Regionally restricted |
4C
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Expression is present in the granule cells.
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Specimen
4D:
postnatal week 10
(more )
Specimen
4D:
(close )
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Genetic Background:
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BALB/c
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Age:
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postnatal week 10
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Sex:
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Male
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: dorsal root ganglion |
Present |
Regionally restricted |
4D
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The most intense expression was in the sensory neurons; there was no apparent signal in the surrounding satellite cells.
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Specimen
4E:
postnatal week 10
(more )
Specimen
4E:
(close )
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Genetic Background:
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BALB/c
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Age:
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postnatal week 10
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Sex:
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Male
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: spinal cord gray matter |
Present |
Regionally restricted |
4F
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4E
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Expression is present in the interneurons and motor neurons, with a particularly strong signal in the large motor neurons of lamina IX. Cells in lamina III-VII, X, and the intermediolateral column also contain expression.
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| TS28: spinal cord dorsal horn |
Present |
Regionally restricted |
4E
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Expression is present in the peptidergic neurons.
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| TS28: spinal cord ependymal layer |
Absent |
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4E
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Analysis Tools