Pou4f1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:88577 Mu X, et al., Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina. Development. 2004 Mar;131(6):1197-210
Assay type:	RNA in situ
MGI Accession ID:	MGI:3522270
Gene symbol:	Pou4f1
Gene name:	POU domain, class 4, transcription factor 1

Probe:	Brn3a probe1
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

3D +/- upper ©

Specimen 3D +/- upper: embryonic day 14.5; Pou4f2^tm3Whk/Pou4f2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS22: retina	Present		3D +/- upper	Expression in retinal progenitor cells.

3D +/- lower ©

Specimen 3D +/- lower: embryonic day 14.5; Pou4f2^tm3Whk/Pou4f2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS22: dorsal root ganglion	Present		3D +/- lower
TS22: spinal cord	Present		3D +/- lower

3D -/- upper ©

Specimen 3D -/- upper: embryonic day 14.5; Pou4f2^tm3Whk/Pou4f2^tm3Whk (more

)

Structure	Level	Pattern	Image	Note
TS22: retina	Weak		3D -/- upper	Expression was reduced in retinal ganglion cells.

3D -/- lower ©

Specimen 3D -/- lower: embryonic day 14.5; Pou4f2^tm3Whk/Pou4f2^tm3Whk (more

)

Structure	Level	Pattern	Image	Note
TS22: dorsal root ganglion	Present		3D -/- lower	Expression in dorsal root ganglia and spinal cord were unaffected.
TS22: spinal cord	Present		3D -/- lower	Expression in dorsal root ganglia and spinal cord were unaffected.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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