Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rgs14tm1Pngr
Name:	regulator of G-protein signaling 14; targeted mutation 1, Josef M Penninger
MGI ID:	MGI:3514019
Gene:	Rgs14  Location: Chr13:55517545-55532500 bp, + strand  Genetic Position: Chr13, 29.8 cM
Alliance:	Rgs14tm1Pngr page

Germline Transmission:	Earliest citation of germline transmission: J:94516
Parent Cell Line:	E14K (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 2 through 9, including the those encoding the RGS-box, were replaced with a PGK-neo construct via homologous recombination. Immunofluorescence confirmed the absence of protein in 1-cell stage zygotes. (J:94516)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rgs14 Mutation:	32 strains or lines available

Original:	J:94516 Martin-McCaffrey L, et al., RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote. Dev Cell. 2004 Nov;7(5):763-9
All:	1 reference(s)