Foxd3 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:93603 Wine-Lee L, et al., Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord. Development. 2004 Nov;131(21):5393-403
Assay type:	RNA in situ
MGI Accession ID:	MGI:3511812
Gene symbol:	Foxd3
Gene name:	forkhead box D3

Probe:	Foxd3 probe2
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

6A ©

6B ©

Specimen 6A/B: embryonic day 11.0 (more

)

Structure	Level	Pattern	Image	Note
TS18: neural tube lateral wall	Present	Regionally restricted	6B , 6A	Expression is in dorsal DI2 interneurons and ventral V1 neurons.

6E ©

6F ©

Specimen 6E/F: embryonic day 11.0; Bmpr1a^tm1Bhr/Bmpr1a^tm2.1Bhr, Bmpr1b^tm1Kml/Bmpr1b^tm1Kml, Tg(Pou3f4-cre)32Cren/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS18: neural tube lateral wall	Present	Regionally restricted	6E , 6F	In the mutant, expression in the DI2 interneuron population is reduced to just a few cells found adjacent to the roof plate. Expression in the ventral VI neurons is unaffected.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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