About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:93603 Wine-Lee L, et al., Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord. Development. 2004 Nov;131(21):5393-403
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3511798
Gene symbol: Msx2
Gene name: msh homeobox 2
Antibody: anti-Msx1/2 (4G1)
Detection system: Biotinylated secondary antibody/[Strept]avidin
Results
Specimen 3C: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: neural tube lateral wall Present Regionally restricted 3C Expression is in the dorsal neural tube.
TS16: neural tube roof plate Present Regionally restricted 3C Expression is in the dorsal neural tube.
Specimen 3D: embryonic day 10.0; Bmpr1atm1Bhr/Bmpr1atm2.1Bhr, Bmpr1btm1Kml/Bmpr1btm1Kml, Tg(Pou3f4-cre)32Cren/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS16: neural tube lateral wall Present Regionally restricted 3D As in wild-type, expression is present in the dorsal neural tube.
TS16: neural tube roof plate Present Regionally restricted 3D As in wild-type, expression is present in the dorsal neural tube.
Specimen not shown Double KO: embryonic day 10.0; Bmpr1atm1Bhr/Bmpr1atm1Bhr (more )
Structure Level Pattern Image Note
TS16: neural tube lateral wall Present Regionally restricted Expression is in the dorsal neural tube. Expression in this mutant is the same as in wild-type embryos.
TS16: neural tube roof plate Present Regionally restricted Expression is in the dorsal neural tube. Expression in this mutant is the same as in wild-type embryos.
Specimen not shown Bmpr1a -/-: embryonic day 10.0; Bmpr1btm1Kml/Bmpr1btm1Kml (more )
Structure Level Pattern Image Note
TS16: neural tube lateral wall Present Regionally restricted Expression is in the dorsal neural tube. Expression in this mutant is the same as in wild-type embryos.
TS16: neural tube roof plate Present Regionally restricted Expression is in the dorsal neural tube. Expression in this mutant is the same as in wild-type embryos.
Specimen 3E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube roof plate Present 3E
TS17: surface ectoderm Present 3E
Specimen 3F: embryonic day 10.5; Bmpr1atm1Bhr/Bmpr1atm2.1Bhr, Bmpr1btm1Kml/Bmpr1btm1Kml, Tg(Pou3f4-cre)32Cren/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: neural tube roof plate Absent 3F Expression is lost in the mutant.
TS17: surface ectoderm Present 3F
Specimen not shown Bmpr1a -/-: embryonic day 10.5; Bmpr1atm1Bhr/Bmpr1atm1Bhr (more )
Structure Level Pattern Image Note
TS17: neural tube roof plate Present Expression in this mutant is the same as in wild-type embryos.
TS17: surface ectoderm Present Expression in this mutant is the same as in wild-type embryos.
Specimen not shown Bmpr1b -/-: embryonic day 10.5; Bmpr1btm1Kml/Bmpr1btm1Kml (more )
Structure Level Pattern Image Note
TS17: neural tube roof plate Present Expression in this mutant is the same as in wild-type embryos.
TS17: surface ectoderm Present Expression in this mutant is the same as in wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory