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Gene Expression Data
Assay Details
Assay
Reference: J:93603 Wine-Lee L, et al., Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord. Development. 2004 Nov;131(21):5393-403
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3511786
Gene symbol: Smad1
Gene name: SMAD family member 1
Antibody: anti-Phospho-Smad1/5/9
Assay notes: The antibody used in this assay recognizes the phosphorylated form of the protein.
Results
Specimen 3A: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: neural tube roof plate Present 3A
TS16: neural tube lateral wall Present Regionally restricted 3A Expression is adjacent to the roof plate.

Specimen 3B: embryonic day 10.0; Bmpr1atm1Bhr/Bmpr1atm2.1Bhr, Bmpr1btm1Kml/Bmpr1btm1Kml, Tg(Pou3f4-cre)32Cren/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS16: neural tube lateral wall Absent 3B Expression has been lost from the dorsal neural tube.
TS16: neural tube roof plate Present Single cells 3B A few expressing cells remain in the roof plate.
TS16: embryo Present Regionally restricted 3B Expression in neural crest cells is unaffected in the mutants.

Specimen not shown Bmpr1a -/-: embryonic day 10.0; Bmpr1atm1Bhr/Bmpr1atm1Bhr (more )
Structure Level Pattern Image Note
TS16: neural tube roof plate Present Expression in this mutant is the same as in wild-type embryos.
TS16: neural tube lateral wall Present Regionally restricted Expression is adjacent to the roof plate. Expression in this mutant is the same as in wild-type embryos.

Specimen not shown Bmpr1b -/-: embryonic day 10.0; Bmpr1btm1Kml/Bmpr1btm1Kml (more )
Structure Level Pattern Image Note
TS16: neural tube roof plate Present Expression in this mutant is the same as in wild-type embryos.
TS16: neural tube lateral wall Present Regionally restricted Expression is adjacent to the roof plate. Expression in this mutant is the same as in wild-type embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory