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Gene Expression Data
Assay Details
Assay
Reference: J:93234 Hecksher-Sorensen J, et al., The splanchnic mesodermal plate directs spleen and pancreatic laterality, and is regulated by Bapx1/Nkx3.2. Development. 2004 Oct;131(19):4665-75
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3510631
Gene symbol: Pdx1
Gene name: pancreatic and duodenal homeobox 1
Antibody: anti-IPF1
Results
Specimen 1D: embryonic day 10.5 (more )
Note: Double labeled: green - Pdx1; red - Tlx1 (assay MGI:3510653).
Structure Level Pattern Image Note
TS17: pancreas primordium Present 1D Expression is in the primordium of the pancreas.
Specimen 1E: embryonic day 10.5 (more )
Note: Double labeled: green - Pdx1; red - Nkx2-5 (assay MGI:3655982).
Structure Level Pattern Image Note
TS17: pancreas primordium Present 1E Expression is in the primordium of the pancreas.
Specimen 2A/B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: pancreas primordium Present 2A , 2B Expression is in the future pancreas.
Specimen 2C: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: pancreas primordium Present 2C Expression is in the future pancreas.
Specimen 2D/E: embryonic day 9.5; Dh/Dh (more )
Structure Level Pattern Image Note
TS16: pancreas primordium Present 2E , 2D Expression is in the mesenchymal cells that will give rise to the pancreas. In this mutant the region is disorganized.
Specimen 3F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: pancreas primordium Present 3F Expression is in the pancreas primordium.
Specimen 3G: embryonic day 10.5; Invsinv/Invsinv (more )
Structure Level Pattern Image Note
TS17: pancreas primordium Present 3G In this embryo the pancreas primordium develops in the opposite direction.
Specimen 4A: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: pancreas primordium Present 4A Expression is in the mesenchyme that will give rise to the pancreas.
Specimen 4B: embryonic day 10.0; Nkx3-2tm1Bobh/Nkx3-2tm1Bobh (more )
Structure Level Pattern Image Note
TS16: pancreas primordium Present 4B Expression is in the mesenchyme that will give rise to the pancreas. In this mutant, the pancreatic bud remains near the midline.
Specimen 4C: embryonic day 10.0; Dh/Dh (more )
Structure Level Pattern Image Note
TS16: pancreas primordium Present 4C Expression is in the mesenchyme that will give rise to the pancreas. In this mutant there is no defined structure.
Specimen 4D: embryonic day 10.5 (more )
Note: Double labeled: green - Pdx1; red - Isl1 (assay MGI:3655984).
Structure Level Pattern Image Note
TS17: pancreas primordium Present 4D Expression is in the mesenchyme that will give rise to the pancreas.
Specimen 4E: embryonic day 10.5; Nkx3-2tm1Bobh/Nkx3-2tm1Bobh (more )
Note: Double labeled: green - Pdx1; red - Isl1 (assay MGI:3655984).
Structure Level Pattern Image Note
TS17: pancreas primordium Present 4E Expression is in the mesenchyme that will give rise to the pancreas. In this mutant, the label stays confined close to the midline.
Specimen 4F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: pancreas primordium Present 4F Expression is in the mesenchyme that will give rise to the pancreas.
Specimen 4G: embryonic day 10.5; Fgf10tm1Ska/Fgf10tm1Ska (more )
Structure Level Pattern Image Note
TS17: pancreas primordium Absent 4G In this mutant, the pancreatic primordium is missing.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory