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Neurog3tm1.1Ggr
Targeted Allele Detail
Summary
Symbol: Neurog3tm1.1Ggr
Name: neurogenin 3; targeted mutation 1.1, Gerard Gradwohl
MGI ID: MGI:3505733
Synonyms: Ngn3EYFP
Gene: Neurog3  Location: Chr10:61968869-61970542 bp, + strand  Genetic Position: Chr10, 32.35 cM, cytoband B4
Alliance: Neurog3tm1.1Ggr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:93570
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA targeting construct was designed to insert an IRES-EYFP and a floxed puromycin resistance cassette downstream of the coding sequence. Crossing with mice expressing Cre in the germ line excised the puromycin resistance gene. (J:93570)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
2 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Neurog3 Mutation:  18 strains or lines available
References
Original:  J:93570 Mellitzer G, et al., Pancreatic islet progenitor cells in neurogenin 3-yellow fluorescent protein knock-add-on mice. Mol Endocrinol. 2004 Nov;18(11):2765-76
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory