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Id4tm1Mais
Targeted Allele Detail
Summary
Symbol: Id4tm1Mais
Name: inhibitor of DNA binding 4; targeted mutation 1, Mark A Israel
MGI ID: MGI:3505549
Synonyms: Id4-, Id4GFP
Gene: Id4  Location: Chr13:48414704-48419502 bp, + strand  Genetic Position: Chr13, 24.71 cM, cytoband B
Alliance: Id4tm1Mais page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:93574
Parent Cell Line:  JM-1 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGFP and a neomycin-resistance gene replaced exons 1 and 2 via homologous recombination. GFP expression was observed in the brain. (J:93574)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 20 assay results
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Id4 Mutation:  8 strains or lines available
References
Original:  J:93574 Yun K, et al., Id4 regulates neural progenitor proliferation and differentiation in vivo. Development. 2004 Nov;131(21):5441-8
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory