Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pax7tm1(cre)Mrc
Name:	paired box 7; targeted mutation 1, Mario R Capecchi
MGI ID:	MGI:3497712
Synonyms:	Pax7-cre, Pax7-ICNCre, Pax7ICNm
Gene:	Pax7  Location: Chr4:139464373-139560839 bp, - strand  Genetic Position: Chr4, 70.83 cM
Alliance:	Pax7tm1(cre)Mrc page

Germline Transmission:	Earliest citation of germline transmission: J:93443
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Pax7tm1(cre)Mrc expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Pax7 (MGI:97491)   Mutation details: An IRES-Cre-FRT-neo-FRT cassette was inserted into the 3' UTR following the stop codon in exon 10. Crossing with mice expressing FLP-e excised the neo. The insertion did not interfere with normal Pax7 function. (J:93443)

Activity:	Tissue activity of this recombinase allele
Driver:	Pax7 (mouse) Summary of all recombinase alleles driven by Pax7. Comparative matrix view of recombinase activities Alliance mouse Pax7 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

32 assay results 3 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Pax7 Mutation:	39 strains or lines available

Original:	J:93443 Keller C, et al., Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin. Genes Dev. 2004 Dec 1;18(21):2608-13
All:	72 reference(s)