Gene Expression Data
Assay Details
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Assay
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Reference:
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J:93240
Brenner O, et al., Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia. Proc Natl Acad Sci U S A. 2004 Dec 9;101(45):16016-21
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3057278
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Gene symbol:
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Mki67
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Gene name:
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antigen identified by monoclonal antibody Ki 67
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Results
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Specimen
1. G.:
postnatal adult
(more  )
Specimen
1. G.:
(close  )
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Genetic Background:
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either: ICR or MF1
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cecum |
Present |
Regionally restricted |
1G
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Expression detected in the crypts of the caecum.
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Specimen
1. H.:
(close )
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Genetic Background:
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either: (involves: 129S1/Sv * 129X1/SvJ * ICR) or (involves: 129S1/Sv * 129X1/SvJ * MF1)
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Mutant Allele(s):
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Runx3tm1Yg/Runx3tm1Yg
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cecum |
Strong |
Regionally restricted |
1H
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Incresed expression detected in the crypts of the caecum compared to the Wild-Type.
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Specimen
not shown:
postnatal year 1
(more )
Specimen
not shown:
(close )
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Genetic Background:
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either: ICR or MF1
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Age:
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postnatal year 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Specimen
not shown:
(close )
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Genetic Background:
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either: (involves: 129S1/Sv * 129X1/SvJ * ICR) or (involves: 129S1/Sv * 129X1/SvJ * MF1)
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Mutant Allele(s):
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Runx3tm1Yg/Runx3tm1Yg
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Age:
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postnatal year 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: stomach |
Strong |
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A marked increase in Mki67 expressing is noted in the knockout.
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Analysis Tools