Tg(TIMP3-lacZ)7Jeb Transgene Detail MGI Mouse (MGI:3056798)

Tg(TIMP3-lacZ)7Jeb
Transgene Detail

Summary

Symbol:	Tg(TIMP3-lacZ)7Jeb
Name:	transgene insertion 7, Jean Bennett
MGI ID:	MGI:3056798
Transgene:	Tg(TIMP3-lacZ)7Jeb Location: unknown
Alliance:	Tg(TIMP3-lacZ)7Jeb page

Transgene
origin

Strain of Origin:

Not Applicable

Transgene
description

Transgene Type:		Transgenic (Reporter)
Mutation:		Insertion
		Mutation details: The transgene contains the beta-galactosidase gene under control of the tissue inhibitor of metalloproteinase 3 (Timp3) promoter. (J:93002)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

Transgenic mice on a B6;SWJ background show no phenotypic defects. lacZ expression is observed in the eye, specifically in the corneal endothelium and ganglion cell layer. lacZ expression is also observed in the kidney, choroid plexus, testes and ovaries, gingiva, bone and the hair follicles of the skin. Transgene expression is developmentally regulated.

References

Original:	J:93002 Zeng Y, et al., Temporal and spatial regulation of gene expression mediated by the promoter for the human tissue inhibitor of metalloproteinases-3 (TIMP-3)-encoding gene. Dev Dyn. 1998 Mar;211(3):228-37
All:	1 reference(s)

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