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Tg(tetL)1Bjd
Transgene Detail
Summary
Symbol: Tg(tetL)1Bjd
Name: transgene insertion 1, Hermann Bujard
MGI ID: MGI:3056776
Synonyms: Tg(tetL)1Uh
Transgene: Tg(tetL)1Bjd  Location: unknown  
Alliance: Tg(tetL)1Bjd page
Transgene
origin
Strain of Origin:  NMRI
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe transgene carries the luciferase gene coupled to a tetracycline-responsive promoter element (TRE). (J:93000)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
Transgenic mice are viable, fertile, and do not display an overt phenotype.

In conjunction with a second transgene expressing the tetracycline-controlled activator proteins tTA or rtTA coupled to a tissue-specific promoter (examples include: Tg(Camk2a-tTA)1Mmay, Tg(Myh6-tTA)6Smbf, and Tg(Nes-rtTA)306Rvs), transgenic mice express luciferase in the appropiate tissue in a tetracycline-inducible fashion.

References
Original:  J:93000 Kistner A, et al., Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proc Natl Acad Sci U S A. 1996 Oct 1;93(20):10933-8
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory