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Tg(TTR-GLVP)1074Tsa
Transgene Detail
Summary
Symbol: Tg(TTR-GLVP)1074Tsa
Name: transgene insertion 1074, Sophia Y Tsai
MGI ID: MGI:3056688
Synonyms: TTR-GLVP
Transgene: Tg(TTR-GLVP)1074Tsa  Location: unknown  
Alliance: Tg(TTR-GLVP)1074Tsa page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(TTR-GLVP)1074Tsa expresses 1 gene
 
Mutation detailsThe transgene construct includes insulator DNA segments (5' region of chicken beta globin gene) flanking both ends of the GLVP transactivator which is driven by the transthyretin enhancer/promoter. The GLVP portion consists of a mutated human progesterone receptor ligand binding domain fused to the yeast GAL4 DNA binding domain and the HSV VP16 transcriptional activation domain. (J:93246)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
Transgenic mice display no phenotypic effects.
References
Original:  J:93246 Wang Y, et al., Ligand-inducible and liver-specific target gene expression in transgenic mice. Nat Biotechnol. 1997 Apr;15(3):239-43
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory