Tg(TTR-GLVP)1074Tsa
Transgene Detail
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Symbol: |
Tg(TTR-GLVP)1074Tsa |
Name: |
transgene insertion 1074, Sophia Y Tsai |
MGI ID: |
MGI:3056688 |
Synonyms: |
TTR-GLVP |
Transgene: |
Tg(TTR-GLVP)1074Tsa Location: unknown
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Alliance: |
Tg(TTR-GLVP)1074Tsa page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(TTR-GLVP)1074Tsa expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
PGR (5241) |
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Mutation details: The transgene construct includes insulator DNA segments (5' region of chicken beta globin gene) flanking both ends of the GLVP transactivator which is driven by the transthyretin enhancer/promoter. The GLVP portion consists of a mutated human progesterone receptor ligand binding domain fused to the yeast GAL4 DNA binding domain and the HSV VP16 transcriptional activation domain.
(J:93246)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Transgenic mice display no phenotypic effects.
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Original: |
J:93246 Wang Y, et al., Ligand-inducible and liver-specific target gene expression in transgenic mice. Nat Biotechnol. 1997 Apr;15(3):239-43 |
All: |
3 reference(s) |
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