Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(H2KePCC)2403Stoe
Name:	transgene insertion 2403, Stephan Oehen
MGI ID:	MGI:3056679
Synonyms:	ePCC
Transgene:	Tg(H2KePCC)2403Stoe  Location: unknown
Alliance:	Tg(H2KePCC)2403Stoe page

Strain of Origin:

C57BL/6 x SJL

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(H2KePCC)2403Stoe expresses 1 gene Transgene expresses: Organism Expressed Gene Note pigeon PCC   Mutation details: Pigeon cytochrome c was engineered for expression in lymphoid tissues of transgenic mice in two forms. The cytochrome C in this construct is targeted to the mitochondria after cytoplasmic synthesis (ePCC). mRNA expression levels are lower in mice carrying this transgene than in mice carrying Tg(H2KmPCC)2939. PCC was expressed in thymus, spleen and LPS stimulated B cells as determined by Northern blot. (J:92997)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:92997 Oehen S, et al., Antigen compartmentation and T helper cell tolerance induction. J Exp Med. 1996 Jun 1;183(6):2617-26
All:	2 reference(s)