Tg(Fos-luc)1Rnd Transgene Detail MGI Mouse (MGI:3056394)

Tg(Fos-luc)1Rnd
Transgene Detail

Summary

Symbol:	Tg(Fos-luc)1Rnd
Name:	transgene insertion 1, Richard N Day
MGI ID:	MGI:3056394
Synonyms:	fos/luc, Fos-luc tg
Transgene:	Tg(Fos-luc)1Rnd Location: unknown
Alliance:	Tg(Fos-luc)1Rnd page

Transgene
origin

Strain of Origin:

(C57BL/6 x C3H)F1 x C57BL/6

Transgene
description

Transgene Type:		Transgenic (Reporter)
Mutation:		Insertion
		The transgene contains a firefly luciferase reporter gene driven by the Fos promoter. (J:93242)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

Transgenic mice on a genetic background that involves C57BL/6J and C3H are viable and fertile.

The luciferase transgene is expressed constitutively in all tissues of these mice, at the lowest levels in kidney, liver, lung, spleen, heart and various areas of the brain, and at the highest levels in skin and testis. Activation of the Fos promoter in response to a wide range of stimuli results in increased luciferase expression.

References

Original:	J:93242 Geusz ME, et al., Long-term monitoring of circadian rhythms in c-fos gene expression from suprachiasmatic nucleus cultures. Curr Biol. 1997 Nov 1;7(10):758-66
All:	2 reference(s)

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