Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Vamp8tm1Hong
Name:	vesicle-associated membrane protein 8; targeted mutation 1, Wanjin Hong
MGI ID:	MGI:3056083
Synonyms:	Vamp8-
Gene:	Vamp8  Location: Chr6:72362204-72367650 bp, - strand  Genetic Position: Chr6, 32.27 cM
Alliance:	Vamp8tm1Hong page

Germline Transmission:	Earliest citation of germline transmission: J:93035
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2, corresponding to amino acids 2-52, was replaced with an IRES-lacZ and floxed PGK-neo cassette. Western blot showed lack of protein in mutants. (J:93035)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vamp8 Mutation:	19 strains or lines available

Original:	J:93035 Wang CC, et al., A role of VAMP8/endobrevin in regulated exocytosis of pancreatic acinar cells. Dev Cell. 2004 Sep;7(3):359-71
All:	22 reference(s)