Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:92174
Aberg T, et al., Runx2 mediates FGF signaling from epithelium to mesenchyme during tooth morphogenesis. Dev Biol. 2004 Jun 1;270(1):76-93
|
|
Assay type:
|
RNA in situ
|
|
MGI Accession ID:
|
MGI:3055862
|
|
Gene symbol:
|
Runx2
|
|
Gene name:
|
runt related transcription factor 2
|
|
Probe:
|
Cbfa1 cDNA7
|
|
Probe preparation:
|
Antisense labelled with S35 RNA
|
|
Visualized with:
|
Autoradiography
|
|
|
Results
|
Specimen
WT E12:
embryonic day 12.5
(more  )
Specimen
WT E12:
(close  )
|
Genetic Background:
|
NMRI
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
WT E13:
embryonic day 13.5
(more )
Specimen
WT E13:
(close )
|
Genetic Background:
|
NMRI
|
|
Age:
|
embryonic day 13.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
WT E14:
embryonic day 14.5
(more )
Specimen
WT E14:
(close )
|
Genetic Background:
|
NMRI
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
Msx1 -/-:
(close )
|
Genetic Background:
|
either: (involves: 129S4/SvJae-Msx1tm1Rilm) or (involves: 129S4/SvJae * BALB/c) or (involves: 129X1/SvJae * C57BL/6J)
|
|
Mutant Allele(s):
|
Msx1tm1Rilm/Msx1tm1Rilm
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
Lef1-/-:
(close )
|
Genetic Background:
|
involves: 129S2/SvPas
|
|
Mutant Allele(s):
|
Lef1tm1Rug/Lef1tm1Rug
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: mandible |
Strong |
|
1F
|
Expression in this mutant is the same as in wild-type embryos.
|
| TS22: maxilla |
Strong |
|
1F
|
Expression in this mutant is the same as in wild-type embryos.
|
| TS22: tooth mesenchyme |
Strong |
|
1F
|
Expression in this mutant is the same as in wild-type embryos.
|
| TS22: dental sac |
Strong |
|
1F
|
Expression is in the dental follicle. Expression in this mutant is the same as in wild-type embryos.
|
Specimen
Eda-/-:
embryonic day 14.5; EdaTa/ EdaTa
(more )
Specimen
Eda-/-:
(close )
|
Genetic Background:
|
B6CBACa Aw-J/A-EdaTa/J-XO
|
|
Mutant Allele(s):
|
EdaTa/EdaTa
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: dental sac |
Strong |
|
1G
|
Expression is in the dental follicle. Expression in this mutant is the same as in wild-type embryos.
|
| TS22: dental papilla |
Strong |
|
1G
|
Expression in this mutant is the same as in wild-type embryos.
|
| TS22: mandible |
Strong |
|
1G
|
Expression in this mutant is the same as in wild-type embryos.
|
| TS22: maxilla |
Strong |
|
1G
|
Expression in this mutant is the same as in wild-type embryos.
|
|
Analysis Tools