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Gene Expression Data
Assay Details
Assay
Reference: J:92862 Grohmann K, et al., Characterization of Ighmbp2 in motor neurons and implications for the pathomechanism in a mouse model of human spinal muscular atrophy with respiratory distress type 1 (SMARD1). Hum Mol Genet. 2004 Sep 15;13(18):2031-42
Assay type: Western blot
MGI Accession ID: MGI:3055358
Gene symbol: Ighmbp2
Gene name: immunoglobulin mu DNA binding protein 2
Antibody: anti-Ighmpb2
Detection system: Secondary antibody coupled to horseradish peroxidase
Results Image: 1A
 Sample Information Bands Other Sample Information
Lane AgeStructure 110 kDa (b) 55 kDa (c) Genetic BackgroundMutant Allele(s)Sex
E15 E15.0 (a) TS23: spinal cord Strong Trace C57BL/6 Not Specified
E18 E18.0 (a) TS26: spinal cord Strong Present C57BL/6 Not Specified
5 days P5 TS28: spinal cord Strong Present C57BL/6 Not Specified
10 days P10 TS28: spinal cord Strong Present C57BL/6 Not Specified
3 weeks P w 3 TS28: spinal cord Present (d) Present C57BL/6 Not Specified
5 weeks P w 5 TS28: spinal cord Not Specified Present C57BL/6 Not Specified
14 weeks P w 14 TS28: spinal cord Not Specified Present C57BL/6 Not Specified
Notes:
(a) Age of embryo at noon of plug day not specified in reference.
(b) This band represents the full length protein.
(c) This band was hardly detectable at E15 but increased in strength after birth.
(d) A strong reduction in expression levels was seen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory