Gene Expression Data
Assay Details
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Assay
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Reference:
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J:59429
Rinkenberger JL, et al., Mcl-1 deficiency results in peri-implantation embryonic lethality. Genes Dev. 2000 Jan 1;14(1):23-7
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:3054241
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Gene symbol:
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Mcl1
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Gene name:
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myeloid cell leukemia sequence 1
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Probe:
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Mcl1 cDNA
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Probe preparation:
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Antisense RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
2a:
embryonic day 3.0
(more  )
Note: Morula.
Specimen
2a:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 3.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Morula.
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Specimen
2b:
embryonic day 4.0
(more )
Note: Blastocyst.
Specimen
2b:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 4.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Blastocyst.
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Specimen
2d:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Mcl1tm1Sjk/Mcl1tm1Sjk
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Age:
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embryonic day 4.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Blastocyst.
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Specimen
2e:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Mcl1tm1Sjk/Mcl1tm1Sjk
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Age:
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embryonic day 4.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Non-compacted blastomere.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS3: 8-cell stage embryo |
Absent |
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2e
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This mutant is delayed and resembles a precompaction 8- to 16-cell blastomere stage embryo instead of a blastocyst.
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Specimen
3a:
embryonic day 5.0
(more )
Note: Implanted blastocyst.
Specimen
3a:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 5.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Implanted blastocyst.
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Specimen
3b:
embryonic day 5.5
(more )
Specimen
3b:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 5.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
3c:
embryonic day 6.5
(more )
Specimen
3c:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 6.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS9: embryo |
Present |
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3c
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| TS28: decidua |
Strong |
Regionally restricted |
3c
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Expression is in the stromal cells proximal to the embryo.
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Analysis Tools