Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(TNNT2-deltaGlu160)17Imeg
Name:	transgene insertion 17, Institute of Molecular Embryology and Genetics
MGI ID:	MGI:3053208
Synonyms:	TgN(cTnT delta Glu160)17Imeg
Transgene:	Tg(TNNT2-deltaGlu160)17Imeg  Location: unknown
Alliance:	Tg(TNNT2-deltaGlu160)17Imeg page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(TNNT2-deltaGlu160)17Imeg expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human TNNT2 (7139) Tnnt2  (MGI:104597)   Mutation details: The transgene encodes a mutant human troponin T2, cardiac having a single-codon, in-frame deletion of the glutamic acid at amino acid position 160. This mutation was identified in affected members of families having dominantly inherited left ventricular hypertrophic cardiomyopathy which, although often mild or subclinical, is associated with a high incidence of sudden death at an early age (J:91746)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:91655 Center for Animal Resources and Development, Information obtained from the Center for Animal Resources and Development (CARD), Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811, Japan. Unpublished. 2004-2103;
All:	2 reference(s)