Tg(TNNT2-deltaGlu160)7Imeg
Transgene Detail
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| Symbol: |
Tg(TNNT2-deltaGlu160)7Imeg |
| Name: |
transgene insertion 7, Institute of Molecular Embryology and Genetics |
| MGI ID: |
MGI:3053183 |
| Synonyms: |
Tg(cTnT delta Glu160)7Imeg, TgN(cTnT delta Glu160)7Imeg |
| Transgene: |
Tg(TNNT2-deltaGlu160)7Imeg Location: unknown
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| Alliance: |
Tg(TNNT2-deltaGlu160)7Imeg page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(TNNT2-deltaGlu160)7Imeg expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
TNNT2 (7139) |
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Mutation details: The transgene encodes a mutant human troponin T2, cardiac having a single-codon, in-frame deletion of the glutamic acid at amino acid position 160. This mutation was identified in affected members of families having dominantly inherited left ventricular hypertrophic cardiomyopathy which, although often mild or subclinical, is associated with a high incidence of sudden death at an early age.
(J:91746)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:91655 Center for Animal Resources and Development, Information obtained from the Center for Animal Resources and Development (CARD), Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811, Japan. Unpublished. 2004-2103; |
| All: |
2 reference(s) |
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Analysis Tools
