Summary | Transgene origin | Transgene description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dspd
Name:	dominant spermiogenesis defect; dominant spermiognenesis defect
MGI ID:	MGI:3052992
Gene:	Dspd  Location: unknown
Alliance:	Dspd page

Strain of Origin:

(C57BL/6 x C3H)F1

Transgene Type:    Transgenic Mutations:    Intergenic deletion, Translocation   Mutation details: A transgene insertion resulted in a translocation between chromosomes 7F and 14C and a deletion on chromosome 7C of at least 1 Mb. This deletion contains at least 6 genes including; Cttn, Fadd, Fgf3, Fgf4, Fgf15, and Ccnd1. The transgene contained a chicken Actb promoter, CMV-IE enhancer and a full length human PEG8 cDNA. Expression of the transgene is not thought to be involved in this phenotype. (J:89381)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dspd Mutation:	1 strain or line available

Original:	J:89381 Kai M, et al., The novel dominant mutation Dspd leads to a severe spermiogenesis defect in mice. Biol Reprod. 2004 Apr;70(4):1213-21
All:	1 reference(s)