Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(FABPCFTR)1Jaw
Name:	transgene insertion 1, Jeffrey A Whitsett
MGI ID:	MGI:3052981
Synonyms:	FABP-hCFTR, Tg(FABPCFTR)#Jaw
Transgene:	Tg(FABPCFTR)1Jaw  Location: unknown
Alliance:	Tg(FABPCFTR)1Jaw page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(FABPCFTR)1Jaw expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human CFTR (1080) Cftr  (MGI:88388)   Mutation details: The transgene contains rat sequences for the fatty acid-binding protein (FABP) promoter and human sequence for the cystic fibrosis transmembrane conductance regulator homolog (CFTR) gene. Expression of the transgene was abundant in the ileum, jejunum, and duodenum and less abundant in the cecum and the colon. (J:21934)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:21934 Zhou L, et al., Correction of lethal intestinal defect in a mouse model of cystic fibrosis by human CFTR. Science. 1994 Dec 9;266(5191):1705-8
All:	57 reference(s)