Summary | Transgene origin | Transgene description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(LckIl4)1315Dbl
Name:	transgene insertion 1315, David Lewis
MGI ID:	MGI:3052795
Transgene:	Tg(LckIl4)1315Dbl  Location: unknown
Alliance:	Tg(LckIl4)1315Dbl page

Strain of Origin:

(C57BL/6J x DBA/2J)F2

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(LckIl4)1315Dbl expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Il4 (MGI:96556)   Mutation details: Transgenic mice overexpress the IL4 transgene under the control of the Lck promoter (lymphocyte protein tyrosine kinase). 8 copies of the transgene were estimated to have integrated into the genome. Expression of the transgene was detected in thymus tissue and by thymocytes. (J:92453)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:92453 Lewis DB, et al., Interleukin 4 expressed in situ selectively alters thymocyte development. J Exp Med. 1991 Jan 1;173(1):89-100
All:	3 reference(s)