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Tmbim6Gt1Jcre
Gene trapped Allele Detail
Summary
Symbol: Tmbim6Gt1Jcre
Name: transmembrane BAX inhibitor motif containing 6; gene trap 1, John C Reed
MGI ID: MGI:3052422
Synonyms: BI-1-
Gene: Tmbim6  Location: Chr15:99290828-99307930 bp, + strand  Genetic Position: Chr15, 56.13 cM, cytoband F3
Alliance: Tmbim6Gt1Jcre page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:91831
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector
 
Mutation detailsThis allele contains a single proviral insertion in reverse orientation between exons 7 and 8. Northern blot demonstrated presence of a truncated transcript present at very low levels in most tissues, except for thymus and lung, where the truncated transcripts were more significant. (J:91831)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tmbim6 Mutation:  20 strains or lines available
References
Original:  J:91831 Chae HJ, et al., BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress. Mol Cell. 2004 Aug 13;15(3):355-66
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory