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Slc17a7tm1Bros
Targeted Allele Detail
Summary
Symbol: Slc17a7tm1Bros
Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7; targeted mutation 1, Nils Brose
MGI ID: MGI:3051945
Synonyms: Slc17a7tm1Rmnd, VGLUT1-
Gene: Slc17a7  Location: Chr7:44813373-44825566 bp, + strand  Genetic Position: Chr7, 29.16 cM
Alliance: Slc17a7tm1Bros page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:89958
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe coding region between the ATG and the fifth coding exon was replaced with a synaptobrevin 2-enhanced yellow fluorescent protein minigene and a floxed neo. Southern blot and PCR confirmed successful targeting. Expression of the EYFP was not detected. (J:89958)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc17a7 Mutation:  39 strains or lines available
References
Original:  J:89958 Wojcik SM, et al., An essential role for vesicular glutamate transporter 1 (VGLUT1) in postnatal development and control of quantal size. Proc Natl Acad Sci U S A. 2004 May 4;101(18):7158-63
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory