Tg(TF-APOE)1Viz
Transgene Detail
|
|
| Symbol: |
Tg(TF-APOE)1Viz |
| Name: |
transgene insertion 1, Vassilis I Zannis |
| MGI ID: |
MGI:2447595 |
| Synonyms: |
TF-ApoE2, TF E2 |
| Transgene: |
Tg(TF-APOE)1Viz Location: unknown
|
| Alliance: |
Tg(TF-APOE)1Viz page
|
|
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Tg(TF-APOE)1Viz expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
APOE (348) |
|
|
|
| |
|
Mutation details: A 4.9 kb genomic fragment containing exons 1 through 4 of the human APOE gene was adjoined to a 690 bp fragment of the human transferrin (TF) gene. RNase protection and Western blot analysis detected epsilon 2 (APOE2) transcript and protein in brain and liver tissues obtained from transgenic mice. Immunohistochemical analysis indicated expression in glial cells
(J:78003)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:78003 Georgopoulos S, et al., Generation and characterization of two transgenic mouse lines expressing human ApoE2 in neurons and glial cells. Biochemistry. 2002 Jul 30;41(30):9293-301 |
| All: |
1 reference(s) |
|
Analysis Tools
