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Tg(Prnp-GFP/cre)1Blw
Transgene Detail
Summary
Symbol: Tg(Prnp-GFP/cre)1Blw
Name: transgene insertion 1, Carrolee Barlow
MGI ID: MGI:3044724
Synonyms: 98030B, 98030B Prion.GFPCre, Cre(+), Prion-Cre, Tg(Prnp-GFP/cre)98030Blw
Transgene: Tg(Prnp-GFP/cre)1Blw  Location: unknown  
Alliance: Tg(Prnp-GFP/cre)1Blw page
Transgene
origin
Strain of Origin:  129S6/SvEvTac
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Prnp-GFP/cre)1Blw expression driven by 1 gene
 
Mutation detailsExpression of an in-frame fusion of cre to GFP was driven by a modified prion promoter. The resulting transgene expresses Cre recombinase in all tissues during embryogenesis including the germline. (J:90777)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Prnp (species not specified)
Summary of all recombinase alleles driven by Prnp.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
This transgene is line 98030B of the laboratory in which the transgene originated. Homozygous transgenic mice are fertile and appear phenotypically normal.
References
Original:  J:90777 Scheel JR, et al., An inbred 129SvEv GFPCre transgenic mouse that deletes loxP-flanked genes in all tissues. Nucleic Acids Res. 2003 May 15;31(10):e57
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory