Tg(Hspa1b-luc)NLF1Rjp
Transgene Detail
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| Symbol: |
Tg(Hspa1b-luc)NLF1Rjp |
| Name: |
transgene insertion NLF1, Jean-Paul Renard |
| MGI ID: |
MGI:3044187 |
| Synonyms: |
HSP70.1 Luc, Hsp70.1 prom./luciferase, NLF 1, NLF1 |
| Transgene: |
Tg(Hspa1b-luc)NLF1Rjp Location: unknown
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| Alliance: |
Tg(Hspa1b-luc)NLF1Rjp page
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: The transgene expresses the cDNA encoding firefly luciferase under control of the heat shock protein 1B (Hsp1b) promoter. This promoter contains four tandem heat shock elements, each recognized by a specific heat shock factor; an inverted CCAAT box; a TATA box; two Sp1 binding sites; and an AP2 binding site. The transgene's expression mirrors that of the endogenous Hsp1b gene during preimplantation embryonic development: both are expressed constitutively at high levels at the 2-cell stage and are inducible from the blastocyst stage forward.
(J:22556)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:22556 Christians E, et al., Expression of the HSP 70.1 gene, a landmark of early zygotic activity in the mouse embryo, is restricted to the first burst of transcription. Development. 1995 Jan;121(1):113-22 |
| All: |
1 reference(s) |
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Analysis Tools
