Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sceltm1Hba
Name:	sciellin; targeted mutation 1, Howard P Baden
MGI ID:	MGI:3044133
Synonyms:	Scel-
Gene:	Scel  Location: Chr14:103750778-103850233 bp, + strand  Genetic Position: Chr14, 52.51 cM, cytoband E
Alliance:	Sceltm1Hba page

Germline Transmission:	Earliest citation of germline transmission: J:100664
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutation:    Disruption caused by insertion of vector   Mutation details: Chimeric mice with this allele were generated by Incyte Genomic Inc, Palo Alto CA. Exons 2 and 3 were replaced with a neomycin resistance gene. This resulted in the deletion of the initiation codon found normally in exon 2. Northern and Western blots failed to detect transcript or protein in mutants, respectively. (J:100664)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Scel Mutation:	45 strains or lines available

Original:	J:100664 Baden HP, et al., Targeted deletion of the sciellin gene resulted in normal development and maturation. Genesis. 2005 Aug;42(4):219-28
All:	1 reference(s)