Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ppp3r1tm2.1Grc
Name:	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I); targeted mutation 2.1, Gerald R Crabtree
MGI ID:	MGI:3044031
Synonyms:	Cnb1delta
Gene:	Ppp3r1  Location: Chr11:17109298-17150380 bp, + strand  Genetic Position: Chr11, 9.71 cM, cytoband A3.1
Alliance:	Ppp3r1tm2.1Grc page

Germline Transmission:	Earliest citation of germline transmission: J:89771
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre-mediated recombination of the single loxP sites in Ppp3r1tm2Grc resulted in the deletion of exons 3 through 5. (J:89771)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

14 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ppp3r1 Mutation:	30 strains or lines available

Original:	J:89771 Neilson JR, et al., Calcineurin B1 is essential for positive but not negative selection during thymocyte development. Immunity. 2004 Mar;20(3):255-66
All:	9 reference(s)