Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Del(11Jmjd6-Mettl23)1Ysfk
Name:	deletion, Chr 11, Yoshinori Fukui 1
MGI ID:	MGI:3043930
Synonyms:	Jmjd6tm1Ysfk, PSR-
Gene:	Del(11Jmjd6-Mettl23)1Ysfk  Location: unknown  Genetic Position: Chr11, Syntenic

Germline Transmission:	Earliest citation of germline transmission: J:90288
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intergenic deletion, Intragenic deletion   Del(11Jmjd6-Mettl23)1Ysfk involves 2 genes/genome features (Jmjd6, Mettl23) View all   Mutation details: A 2.8 kb segment including exons 1, 2 and part of exon 3 was replaced with a neo cassette via homologous recombination. Northern blot analysis confirmed the absence of RNA expression in homozygotes. A subsequent publication demonstrated that the neo cassette also replaced the first exon of the neighboring gene, Mettl23, located on the opposite strand. RT-PCR confirmed absence of Mettl23 mRNA in homozygous embryos. (J:90288, J:137989)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	3 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(11Jmjd6-Mettl23)1Ysfk Mutation:	0 strains or lines available

Original:	J:90288 Kunisaki Y, et al., Defective fetal liver erythropoiesis and T lymphopoiesis in mice lacking the phosphatidylserine receptor. Blood. 2004 May 1;103(9):3362-4
All:	4 reference(s)