Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nbl1tm1Saki
Name:	NBL1, DAN family BMP antagonist; targeted mutation 1, S Sakiyama
MGI ID:	MGI:3042574
Synonyms:	Dan-
Gene:	Nbl1  Location: Chr4:138809595-138820304 bp, - strand  Genetic Position: Chr4, 70.57 cM, cytoband D3
Alliance:	Nbl1tm1Saki page

Germline Transmission:	Earliest citation of germline transmission: J:89353
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 2.5 kb fragment including exons 2 and 3 was replaced with an MC1-Neo cassette. RT-PCR confirmed the absence of RNA expression in homozygotes. (J:89353)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nbl1 Mutation:	16 strains or lines available

Original:	J:89353 Ohtori S, et al., Reduced inflammatory pain in mice deficient in the differential screening-selected gene aberrative in neuroblastoma. Mol Cell Neurosci. 2004 Mar;25(3):504-14
All:	1 reference(s)