Bmp10tm1Shou
Targeted Allele Detail
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Symbol: |
Bmp10tm1Shou |
Name: |
bone morphogenetic protein 10; targeted mutation 1, Weinian Shou |
MGI ID: |
MGI:3042354 |
Synonyms: |
BMP10- |
Gene: |
Bmp10 Location: Chr6:87405976-87411494 bp, + strand Genetic Position: Chr6, 37.96 cM, cytoband D2
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Alliance: |
Bmp10tm1Shou page
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Absent vitelline vessels in the yolk sac, stalled vascular development at the primary capillary plexus stage, and arteriovenous malformation in Bmp10tm1Shou/Bmp10tm1Shou embryos
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:89476
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Parent Cell Line: |
CCE916 (ES Cell)
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Strain of Origin: |
129S/SvEv
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exons 1 and 2 were deleted and replaced with a PGK-neo cassette via homologous recombination. RT-PCR confirmed the absence of expression in homozygotes.
(J:89476)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Bmp10 Mutation: |
21 strains or lines available
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Original: |
J:89476 Chen H, et al., BMP10 is essential for maintaining cardiac growth during murine cardiogenesis. Development. 2004 May;131(9):2219-31 |
All: |
4 reference(s) |
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