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Gene Expression Data
Assay Details
Assay
Reference: J:89153 Ang SJ, et al., Spatial and temporal expression of Wnt and Dickkopf genes during murine lens development. Gene Expr Patterns. 2004 May;4(3):289-95
Assay type: RNA in situ
MGI Accession ID: MGI:3042107
Gene symbol: Wnt7b
Gene name: wingless-type MMTV integration site family, member 7B
Probe: Wnt7b cDNA4
Probe preparation: Antisense labelled with digoxigenin RNA
Assay notes: The lens development data is summarized in Table 1.
Results
Specimen Table 1, Wnt7b: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: lens placode Weak

Specimen 2, A1: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future brain Weak 2A1
TS15: head mesenchyme Weak 2A1
TS15: surface ectoderm Weak Regionally restricted 2A1 Shown is expression in the ectoderm of the head.

Specimen 2, B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lens pit Present 2B
TS17: optic cup Present Regionally restricted 2B Expression is in the retinal primordia.
TS17: brain Weak 2B
TS17: head mesenchyme Weak 2B
TS17: surface ectoderm Weak Regionally restricted 2B Shown is expression in the ectoderm of the head.

Specimen 2, B1: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lens pit Present 2B1
TS17: optic cup Present Regionally restricted 2B1 Expression is in the retinal primordia.
TS17: brain Present 2B1
TS17: head mesenchyme Present 2B1
TS17: surface ectoderm Present Regionally restricted 2B1 Shown is expression in the ectoderm of the head.

Specimen 2, C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cornea Present 2C
TS20: hyaloid vascular plexus Present 2C
TS20: lens vesicle Strong Regionally restricted 2C Expression is in the elongating primary fibers.
TS20: lens vesicle epithelium Strong 2C

Specimen 2, C1: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cornea Present 2C1
TS20: hyaloid vascular plexus Present 2C1
TS20: lens vesicle Strong Regionally restricted 2C1 Expression is in the elongating primary fibers.
TS20: lens vesicle epithelium Strong 2C1

Specimen 2, D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lens fiber Strong 2D

Specimen 2, D1: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lens fiber Strong 2D1

Specimen 2, E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lens fiber Strong 2E

Specimen 2, E1: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lens fiber Strong 2E1

Specimen 2, F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lens fiber Weak Regionally restricted 2F Expression is in the cortical fibers.

Specimen 2, F1: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lens fiber Weak Regionally restricted 2F1 Expression is in the cortical fibers.

Specimen 2, G: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: lens epithelium Present 2G
TS27: lens Present Regionally restricted 2G Expression is in the equatorial region and weak expression in the cortical fibers.

Specimen 2, G1: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: lens epithelium Present 2G1
TS27: lens Present Regionally restricted 2G1 Expression is in the equatorial region and weak expression in the cortical fibers.

Specimen 2, H: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: lens epithelium Present 2H
TS28: lens Present Regionally restricted 2H Expression is in the equatorial region and is absent in the fibers.

Specimen 2, H1: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: lens epithelium Present 2H1
TS28: lens Present Regionally restricted 2H1 Expression is in the equatorial region and is absent in the fibers.

Specimen 2, I: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: lens epithelium Present Graded 2I Expression is weaker in the central epithelium.
TS28: lens Present Regionally restricted 2I Expression is in the equatorial region.

Specimen 2, I1: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: lens epithelium Present Graded 2I1 Expression is weaker in the central epithelium.
TS28: lens Present Regionally restricted 2I1 Expression is in the equatorial region.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory