Tg(Col1a1-cre)1Kry
Transgene Detail
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Symbol: |
Tg(Col1a1-cre)1Kry |
Name: |
transgene insertion 1, Gerard Karsenty |
MGI ID: |
MGI:3041864 |
Synonyms: |
2.3kb alpha1(I)-cre, alpha1(1) collagen-Cre, alpha1(I)collagen-Cre, alpha1(I)-Cre, Col1a12.3kbCre, Col1-Cre, Col2.3-Cre, Col-Cre |
Transgene: |
Tg(Col1a1-cre)1Kry Location: unknown Genetic Position: Chr14, Syntenic
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Alliance: |
Tg(Col1a1-cre)1Kry page
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(Col1a1-cre)1Kry expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
Not Specified |
Col1a1 |
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Mutation details: Sequence encoding cre recombinase was adjoined to 2.3 kb of the Col1a1 promoter. The endogenous Col1a1 promoter is active in osteoblasts throughout their differentiation and, accordingly, expression of cre recombinase was detected exclusively in bone. Cytogenetic mapping indicates that the transgene integrated on chromosome 14qE2-4.
(J:77071, J:165282)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Col1a1
(species not specified)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
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Original: |
J:77071 Dacquin R, et al., Mouse alpha1(I)-collagen promoter is the best known promoter to drive efficient Cre recombinase expression in osteoblast. Dev Dyn. 2002 Jun;224(2):245-51 |
All: |
147 reference(s) |
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