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Gene Expression Data
Assay Details
Assay
Reference: J:56361 Kimura N, et al., A novel mammalian T-box-containing gene, Tbr2, expressed in mouse developing brain. Brain Res Dev Brain Res. 1999 Jun 2;115(2):183-93
Assay type: RNA in situ
MGI Accession ID: MGI:3041733
Gene symbol: Eomes
Gene name: eomesodermin
Probe: Tbr2 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3b: embryonic day 14.5 (more )
Note: Ventral view.
Structure Level Pattern Image Note
TS22: hindbrain Present 3b
TS22: midbrain Present 3b
TS22: olfactory lobe Present 3b Expression is present in the olfactory bulb.

Specimen 3d: embryonic day 14.5 (more )
Note: Dorsal view.
Structure Level Pattern Image Note
TS22: hindbrain Present 3d
TS22: midbrain Present 3d
TS22: olfactory lobe Present 3d Expression is present in the olfactory bulb.
TS22: cerebral cortex Present Regionally restricted 3d Expression is present in the ventro-caudal region.
TS22: telencephalon Present Regionally restricted 3d There is no expression in the ventral telencephalon.

Specimen E11.5 brain: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: brain Present Regionally restricted Expression is present in the posterior part of the brain.

Specimen 3f: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 3f
TS19: hindlimb bud Present 3f

Specimen 3h: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hindlimb digit Present 3h

Specimen E14.5 forelimb: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forelimb digit Present

Specimen 4Aa: embryonic day 14.5 (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS22: olfactory lobe Present Regionally restricted 4Aa Expression is present in the region of the olfactory bulb that will give rise to the mitral and glomerular cell layers. It is not detected in the neuroepithelium.

Specimen 4Af: embryonic day 14.5 (more )
Note: Sagittal section.
Structure Level Pattern Image Note
TS22: olfactory lobe Present Regionally restricted 4Af Expression is present in the region of the olfactory bulb that will give rise to the mitral and glomerular cell layers. It is not detected in the neuroepithelium.

Specimen 4Ab: embryonic day 14.5 (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS22: caudate nucleus Present 4Ab Expression is present in the caudate putamen.
TS22: forebrain Present Regionally restricted 4Ab Expression is present in the forebrain in regions spreading from the caudate putamen to the piriform cortex.
TS22: olfactory cortex Present Regionally restricted 4Ab Expression is present in the forebrain in regions spreading from the caudate putamen to the piriform cortex.

Specimen 4Ag: embryonic day 14.5 (more )
Note: Sagittal section.
Structure Level Pattern Image Note
TS22: caudate nucleus Present 4Ag Expression is present in the caudate putamen.
TS22: forebrain Present Regionally restricted 4Ag Expression is present in the forebrain in regions spreading from the caudate putamen to the piriform cortex. There is weak expression in the primordium of the hippocampus.
TS22: olfactory cortex Present 4Ag

Specimen 4Ac: embryonic day 14.5 (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS22: midbrain mantle layer Strong Regionally restricted 4Ac There is strong expression in the central gray substance.
TS22: midbrain tegmentum Strong Regionally restricted 4Ac There is strong expression in the oculomotor nuclei.

Specimen 4Ah: embryonic day 14.5 (more )
Note: Sagittal section.
Structure Level Pattern Image Note
TS22: pons Strong Regionally restricted 4Ah There is strong expression in the motor and spinal tract nuclei of the trigeminal nerve.

Specimen 4Ad: embryonic day 14.5 (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS22: midbrain mantle layer Strong Regionally restricted 4Ad There is strong expression in the red nuclei.
TS22: midbrain tegmentum Strong Regionally restricted 4Ad There is strong expression in the oculomotor nuclei.

Specimen 4Ai: embryonic day 14.5 (more )
Note: Sagittal section.
Structure Level Pattern Image Note
TS22: pons Strong Regionally restricted 4Ai There is strong expression in the vestibular nuclei.

Specimen 4Ae: embryonic day 14.5 (more )
Note: Coronal section.
Structure Level Pattern Image Note
TS22: pons Strong Regionally restricted 4Ae There is strong expression in the lateral lemniscus.

Specimen 4Aj: embryonic day 14.5 (more )
Note: Sagittal section.
Structure Level Pattern Image Note
TS22: pons Strong Regionally restricted 4Aj There is strong expression in the facial nuclei.
TS22: medulla oblongata Strong Regionally restricted 4Aj There is strong expression in the hypoglossal nuclei.

Specimen E14.5 midbrain: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: midbrain Present Expression extends caudally to the rhombencephalic region.

Specimen 5a: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: olfactory lobe Present Regionally restricted 5a Expression is present in the glomerular and mitral cell layers.

Specimen 5d: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: dentate gyrus Present Regionally restricted 5d Expression was present in the granule cell layer.
TS26: hippocampus Present Regionally restricted 5d Expression is present in the pyramidal layer of CA1-CA3.
TS26: midbrain Absent 5d There is no expression in the nuclei were expression was so strong earlier in development.

Specimen 5b: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 5b Expression is present in the glomerular and mitral cell layers.

Specimen 5e: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present Regionally restricted 5e Expression was present in the granule cell layer.
TS28: hippocampus Present Regionally restricted 5e Expression is present in the pyramidal layer of CA1-CA3.
TS28: midbrain Absent 5e There is no expression in the nuclei were expression was so strong earlier in development.

Specimen 5c: postnatal adult (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 5c Expression is present in the glomerular and mitral cell layers.

Specimen 5f: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present Regionally restricted 5f Expression was present in the granule cell layer.
TS28: hippocampus Present Regionally restricted 5f Expression is present in the pyramidal layer of CA1-CA3.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory