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Gene Expression Data
Assay Details
Assay
Reference: J:89198 Christoffels VM, et al., T-box transcription factor Tbx2 represses differentiation and formation of the cardiac chambers. Dev Dyn. 2004 Apr;229(4):763-70
Assay type: RNA in situ
MGI Accession ID: MGI:3041470
Gene symbol: Tbx2
Gene name: T-box 2
Probe: Tbx2 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1B: embryonic day 8.75 (more )
Structure Level Pattern Image Note
TS14: primitive ventricle cardiac muscle Absent 1B
TS14: atrioventricular canal Present 1B
TS14: common atrial chamber cardiac muscle Present 1B
TS14: outflow tract endocardial tube Present 1B
Specimen 1E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: atrioventricular canal Present 1E
TS15: outflow tract endocardial tube Present 1E
TS15: endocardial cushion Present Graded 1E
TS15: common atrial chamber cardiac muscle Present Regionally restricted 1E Only the inner curvatures showed expression.
TS15: primitive ventricle cardiac muscle Present Regionally restricted 1E Only the inner curvatures showed expression.
Specimen 1J: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: atrioventricular canal Present 1J
Specimen 1L: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: atrioventricular canal Present 1L
TS17: common atrial chamber cardiac muscle Absent 1L
TS17: primitive ventricle cardiac muscle Absent 1L
Specimen 1N: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: atrioventricular canal Present Regionally restricted 1N Expression overlaps with Tbx2 and Tbx4.
TS17: outflow tract Present Regionally restricted 1N Expression overlaps with Tbx2 and Tbx4.
Specimen 2E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: body wall mesenchyme Present Regionally restricted 2E Expression is ventral.
TS20: atrioventricular endocardial cushion Present 2E
TS20: outflow tract Present Regionally restricted 2E Expression is in the cushion mesenchyme.
TS20: atrioventricular canal Present Regionally restricted 2E Expression is in the myocardium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory