Summary | Transgene origin | Transgene description | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(MMTVTGFA)254Rjc
Name:	transgene insertion 254, Robert J Coffey
MGI ID:	MGI:3040319
Transgene:	Tg(MMTVTGFA)254Rjc  Location: unknown
Alliance:	Tg(MMTVTGFA)254Rjc page

Strain of Origin:

(C57BL/6 x DBA/2)F2

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(MMTVTGFA)254Rjc expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human TGFA (7039) Tgfa  (MGI:98724)   Mutation details: The transgene contains the mouse mammary tumor virus LTR and the normal allele of the human transforming growth factor alpha gene. The vector also contains exons 2 and 3 of the rabbit beta-globin gene. Lines 254, 257, 64 and 29 were produced. (J:28453)

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Tg(MMTVTGFA)254Rjc

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available

Original:	J:72085 Halter SA, et al., Distinctive patterns of hyperplasia in transgenic mice with mouse mammary tumor virus transforming growth factor-alpha. Characterization of mammary gland and skin proliferations. Am J Pathol. 1992 May;140(5):1131-46
All:	12 reference(s)