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Tg(IgTp-myc)11Yik
Transgene Detail
Summary
Symbol: Tg(IgTp-myc)11Yik
Name: transgene insertion 11, Yoji Ikawa
MGI ID: MGI:3039692
Transgene: Tg(IgTp-myc)11Yik  Location: unknown  
Alliance: Tg(IgTp-myc)11Yik page
Transgene
origin
Strain of Origin:  (C57BL/6CrSlc x CD-1)F1
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThis transgene contains the simian virus 40 early gene promoter and an allele of the human avian myelocytomatosis virus oncogene homolog that contains a deletion of exon 1 and part of intron 1. The construct also contains mouse immunoglobulin heavy chain enhancer sequences. (J:46455)
Tumor Data
List all tumor models in MMHCdb carrying Tg(IgTp-myc)11Yik
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Multiple lines were produced differing in copy number, penetrance, litter size, and tumor incidence.
References
Original:  J:46455 Suda Y, et al., Driven by the same Ig enhancer and SV40 T promoter ras induced lung adenomatous tumors, myc induced pre-B cell lymphomas and SV40 large T gene a variety of tumors in transgenic mice. EMBO J. 1987 Dec 20;6(13):4055-65
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory