Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Llgl1tm1Vv
Name:	LLGL1 scribble cell polarity complex component; targeted mutation 1, Valeri Vasioukhin
MGI ID:	MGI:3039268
Gene:	Llgl1  Location: Chr11:60590549-60605012 bp, + strand  Genetic Position: Chr11, 37.81 cM
Alliance:	Llgl1tm1Vv page

Germline Transmission:	Earliest citation of germline transmission: J:89028
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: The exon immediately downstream of the first coding exon was left flanked by single loxP sites following cre-mediated excision of an IRES-betageo cassette used for selection. (J:89028)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	33 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Llgl1 Mutation:	63 strains or lines available

Original:	J:89028 Klezovitch O, et al., Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice. Genes Dev. 2004 Mar 1;18(5):559-71
All:	15 reference(s)