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Tg(Tec-BCR/ABL1)3Hhi
Transgene Detail
Summary
Symbol: Tg(Tec-BCR/ABL1)3Hhi
Name: transgene insertion 3, Hisamaru Hirai
MGI ID: MGI:3039032
Transgene: Tg(Tec-BCR/ABL1)3Hhi  Location: unknown  
Alliance: Tg(Tec-BCR/ABL1)3Hhi page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F2
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Tec-BCR/ABL1)3Hhi expresses 2 genes
 
Tg(Tec-BCR/ABL1)3Hhi expression driven by 1 gene
 
Mutation details: Fusion gene of human BCR and ABL1 encoding an oncogenic 210 kDa protein (p210BCR/ABL). Expression of the cDNA is controlled by the mouse Tec promoter. (J:46392)
Tumor Data
List all tumor models in MMHCdb carrying Tg(Tec-BCR/ABL1)3Hhi
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
The original paper describes the founder of this line.
References
Original:  J:46392 Honda H, et al., Development of acute lymphoblastic leukemia and myeloproliferative disorder in transgenic mice expressing p210bcr/abl: a novel transgenic model for human Ph1-positive leukemias. Blood. 1998 Mar 15;91(6):2067-75
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory