Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Foxo3Gt(VICTR20)1Kca
Name:	forkhead box O3; gene trap 1, Karen C Arden
MGI ID:	MGI:3038979
Synonyms:	Foxo3a-, Foxo3Kca
Gene:	Foxo3  Location: Chr10:42057841-42152691 bp, - strand  Genetic Position: Chr10, 22.79 cM
Alliance:	Foxo3Gt(VICTR20)1Kca page

Germline Transmission:	Earliest citation of germline transmission: J:88638
Parent Cell Line:	Lex-1 (ES Cell)
Strain of Origin:	129S5/SvEvBrd

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector   Mutation details: A retroviral gene trap vector was inserted into intron 1. Western blot analysis confirmed the absence of protein expression in homozygotes (J:88638)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxo3 Mutation:	48 strains or lines available

Original:	J:88638 Hosaka T, et al., Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification. Proc Natl Acad Sci U S A. 2004 Apr 2;101(9):2975-80
All:	8 reference(s)