About   Help   FAQ
Nr4a3tm1Omc
Targeted Allele Detail
Summary
Symbol: Nr4a3tm1Omc
Name: nuclear receptor subfamily 4, group A, member 3; targeted mutation 1, Orla M Conneely
MGI ID: MGI:3037444
Synonyms: nor-1-
Gene: Nr4a3  Location: Chr4:48045153-48086447 bp, + strand  Genetic Position: Chr4, 26.07 cM, cytoband B2
Alliance: Nr4a3tm1Omc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:73971
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA lacZ gene and neomycin selection cassette were inserted into exon 2. Beta-galactosidase was expressed from this allele in a pattern similar to the endogenous gene. (J:73971)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nr4a3 Mutation:  53 strains or lines available
References
Original:  J:73971 Ponnio T, et al., The nuclear receptor Nor-1 is essential for proliferation of the semicircular canals of the mouse inner ear. Mol Cell Biol. 2002 Feb;22(3):935-45
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/09/2024
MGI 6.23
The Jackson Laboratory