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Osr2tm1Jian
Targeted Allele Detail
Summary
Symbol: Osr2tm1Jian
Name: odd-skipped related 2; targeted mutation 1, Rulang Jiang
MGI ID: MGI:3033240
Gene: Osr2  Location: Chr15:35296244-35303451 bp, + strand  Genetic Position: Chr15, 14.46 cM
Alliance: Osr2tm1Jian page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94755
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 2.6 kb segment containing Exons 2, 3 and art of 4 was replaced with a lacZ and neomycin resistance cassette. This includes most of the coding region. (J:94755)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 41 assay results
2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Osr2 Mutation:  17 strains or lines available
References
Original:  J:94755 Lan Y, et al., Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis. Development. 2004 Jul;131(13):3207-16
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory