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Gene Expression Data
Assay Details
Assay
Reference: J:68163 Loes S, et al., Expression of class 3 semaphorins and neuropilin receptors in the developing mouse tooth. Mech Dev. 2001 Mar;101(1-2):191-4
Assay type: RNA in situ
MGI Accession ID: MGI:3032946
Gene symbol: Sema3a
Gene name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
Probe: Sema3a probe
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1A1: embryonic day 10.5 (more )
Note: Initiation stage of tooth development.
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component ectoderm Strong Regionally restricted 1A1 Expression is in the dental epithelium.
TS17: 1st branchial arch maxillary component ectoderm Strong Regionally restricted 1A1 Expression is in the dental epithelium.

Specimen 1A2: embryonic day 11.5 (more )
Note: Initiation stage of tooth development.
Structure Level Pattern Image Note
TS19: mandibular process Present Regionally restricted 1A2 Expression is in the dental epithelium and the presumptive dental mesenchyme.
TS19: maxillary process Present Regionally restricted 1A2 Expression is in the dental epithelium and the presumptive dental mesenchyme.

Specimen 1A3: embryonic day 12.5 (more )
Note: Early bud stage of tooth development.
Structure Level Pattern Image Note
TS20: tooth bud Present Regionally restricted 1A3 Expression is in the dental epithelium and the presumptive dental mesenchyme.

Specimen 1A4: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: primary enamel knot Present 1A4
TS21: tooth epithelium Present 1A4
TS21: tooth bud Present 1A4
TS21: tooth mesenchyme Present 1A4

Specimen 1A5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: enamel organ Absent 1A5
TS22: tooth mesenchyme Present Regionally restricted 1A5 Expression is in some cells underlying the inner dental epithelium.
TS22: cap stage tooth Present Regionally restricted 1A5

Specimen 1A6: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: dental papilla Present Regionally restricted 1A6 Expression is in the preodontoblasts.
TS24: tooth mesenchyme Present Regionally restricted 1A6 Expression is in the mesenchyme underlying the preodontoblasts.
TS24: bell stage tooth Present Regionally restricted 1A6

Specimen 1A7: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: dental papilla Present Regionally restricted 1A7 Expression is in the preodontoblasts.
TS26: tooth mesenchyme Present Regionally restricted 1A7 Expression is in the mesenchyme underlying the preodontoblasts.
TS26: bell stage tooth Present Regionally restricted 1A7
TS26: dental sac Present 1A7
TS26: enamel organ Present Regionally restricted 1A7 Expression is in the region of the epithelial cervical loops.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory