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Gene Expression Data
Assay Details
Assay
Reference: J:68163 Loes S, et al., Expression of class 3 semaphorins and neuropilin receptors in the developing mouse tooth. Mech Dev. 2001 Mar;101(1-2):191-4
Assay type: RNA in situ
MGI Accession ID: MGI:3032945
Gene symbol: Nrp2
Gene name: neuropilin 2
Probe: Npn2 probe2
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1F1: embryonic day 10.5 (more )
Note: Initiation stage of tooth development.
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component Present Regionally restricted 1F1 Expression is in the dental epithelium and presumptive dental mesenchyme.
TS17: 1st branchial arch maxillary component Present Regionally restricted 1F1 Expression is in the dental epithelium and presumptive dental mesenchyme.
Specimen 1F2: embryonic day 11.5 (more )
Note: Initiation stage of tooth development.
Structure Level Pattern Image Note
TS19: dental placode Absent 1F2 Absent in the tooth primordium.
Specimen 1F3: embryonic day 12.5 (more )
Note: Early bud stage of tooth development.
Structure Level Pattern Image Note
TS20: tooth Present Regionally restricted 1F3 Some transcripts are in the dental mesenchyme.
Specimen 1F4: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: primary enamel knot Strong 1F4
TS21: tooth bud Strong 1F4
TS21: tooth mesenchyme Strong 1F4
Specimen 1F5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tooth epithelium Present Regionally restricted 1F5 Expression is in the epithelium next to the enamel knot.
TS22: dental papilla Weak 1F5
TS22: cap stage tooth Present 1F5
Specimen 1F6: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: dental papilla Present Regionally restricted 1F6 Expression is in the coronal regions.
TS24: bell stage tooth Present 1F6
TS24: dental sac Present 1F6
TS24: inner enamel epithelium Present 1F6
TS24: stratum intermedium Present 1F6
Specimen 1F7: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: bell stage tooth Present Regionally restricted 1F7 Expression is in the cervical loops.
TS26: dental sac Present 1F7
TS26: inner enamel epithelium Present 1F7
TS26: stratum intermedium Present 1F7
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory