Gene Expression Data
Assay Details
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Assay
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Reference:
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J:87397
Sumazaki R, et al., Conversion of biliary system to pancreatic tissue in Hes1-deficient mice. Nat Genet. 2004 Jan;36(1):83-7
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3029195
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Gene symbol:
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Isl1
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Gene name:
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ISL1 transcription factor, LIM/homeodomain
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Antibody:
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clone 39.4D5
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Detection system:
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Secondary antibody coupled to Alexa Fluor 488
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Assay notes:
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The secondary antibody for this assay may have been MGI:1314839.
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Results
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Specimen
c E12.5 Isl1/CA:
embryonic day 12.5
(more  )
Specimen
c E12.5 Isl1/CA:
(close  )
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Genetic Background:
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CD-1
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Specimen
j E12.5 Isl1/CA:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Mutant Allele(s):
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Hes1tm1Fgu/Hes1tm1Fgu
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: common bile duct |
Present |
Single cells |
4j
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Expression of this marker indicates ectopic differentiation of pancreatic beta cells in the common bile duct.
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Specimen
q E12.5 Insulin/Isl1:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Mutant Allele(s):
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Hes1tm1Fgu/Hes1tm1Fgu
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Age:
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embryonic day 16.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: common bile duct |
Present |
Single cells |
4q
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Expression of this marker indicates ectopic differentiation of pancreatic beta cells in the common bile duct. The cells coexpress Isl1 and insulin.
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Analysis Tools